<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW083 sw083 South Africa 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI+LPV 91

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T215Y V75VA     E44ED, S48T, V118VI, K122E, D123G, S162Y, K173T, Q174R, D177E, T200A, E203EK, Q207E, R211K, V245Q K65KM
>sw083| codons 40-247
ELEKDGKITKIGPENPYNTPVFAIKMKNSTKWRKLADFRELNKRTQDFWEVQLGIPHPAG
LKKKKSVTVLDVGDAYFSIPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAI
FQYSMTKILEPFRTRNPEIVIYQYMDDLYVGSDLEIGQHRAKIKELREHLLKWGFYTPDK
KHQKEPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V82A   T12S, I15V, L19I, K20R, M36I, R41K, L63P, H69K, L89M, I93L  
>sw083| codons 4-99
TLWQRPLVSIKVGGQIREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIP
IEICGKKAIGTVLVGPTPANIIGRNMLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008