<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW081 SW081 South Africa 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI+EFV NA
2 3TC+AZT+NVP 97

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19V, M36I, R41K, H69K, V82I, L89M, I93L  
>SW081| codons 4-99
TLWQRPLVSIKVGGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, K70R, M184V, T215F K219Q K103N, V106M, M230L Y188F K122E, D123N, I142V, M164L, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, L228H, V245Q Q197T
>SW081| codons 40-247
ELEKEGKISKIGPENPYNTPVFAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LKKNKSMTVLDVGDAYFSVPLDENFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAI
FQSSLTKILEPFRAKNPEIVIYQYVDDLFVGSDLEIGTHRAKIEELREHLLKWGLFTPDQ
KHQKEPPFHWLGYELHPDKWTVQPIQLP

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008