<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW077 SW077 South Africa 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 26

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, L19V, M36I, R41K, L63A, H69K, L89M, I93L  
>SW077| codons 4-99
TLWQRPLVSIKIGGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIA
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, M184V   K103KN, V106M, Y188YC   S48T, V60I, K122E, D123S, T165L, K173A, Q174K, D177E, I178L, G196E, T200A, Q207E, Q242L, V245Q  
>SW077| codons 40-247
EMEKEGKITKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LKKNKSMTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAI
FQSSMLKILEPFRAKNPELVIYQYVDDLCVGSDLEIEQHRAKIEELREHLLRWGFTTPDK
KHQKEPPFLWMGYELHPDKWTVLPIQLP

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008