Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SW074 | SW074 | South Africa | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | 100 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | V108VI | S48T, V60I, S68G, V90I, D121Y, K122E, I135T, S162Y, K173S, Q174K, D177E, I178L, V179I, G196E, T200A, Q207E, R211K, V245Q | K101G |
| >SW074| codons 40-247 EMEKEGKITKIGPENPYNTPIFAIKKKDGTKWRKLVDFRELNKRTQDFWEIQLGIPHPAG LGKNKSVTILDVGDAYFSVPLYEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAI FQYSMTKILEPFRSKNPELIIYQYVDDLYVGSDLEIEQHRAKIEELREHLLKWGFTTPDK KHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19I, M36I, R41K, H69K, L89M, I93L |
| >SW074| codons 4-99 TLWQRPLVTIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |