<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW073 SW073 South Africa 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI NA
2 3TC+AZT+NVP 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, Q151M V75I K103N A98G, V108I V60I, S68G, K122E, D123G, I132L, K173A, Q174K, D177E, T200A, I202V, Q207E, R211K, F214L, Q242P, V245R  
>SW073| codons 40-247
EMEKEGKISKIGPENPYNTPIFAIKRKDGTKWRKLIDFRELNKRTQDFWEVQLGIPHPGG
LKKNKSVTILDVGDAYFSVPLDEGFRKYTAFTLPSINNETPGIRYQYNVLPMGWKGSPAI
FQSSMTKILEPFRAKNPEIVIYQYMDDLYVGSDLEIGQHRAKVEELREHLLKWGLTTPDK
KHQKEPPFLWMGYELHPDKWTVPPIRLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15S, G16R, L19I, E35D, M36I, R41K, H69K, T74S, L89M, I93L I13N
>SW073| codons 4-99
TLWQRPLVTNKSRGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008