<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW070 SW070 South Africa 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 52
2 3TC+AZT+LPV 49

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R     E138K, V179D S48T, V60I, K103R, V106I, K122E, D123N, I135M, K173A, Q174K, D177E, T200A, Q207D, R211K, F214L, V245Q  
>SW070| codons 40-247
EMEKEGKITKIGPENPYNTPIFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LKKRKSITVLDVGDAYFSVPLDENFRKYTAFTIPSMNNKTPGIRYQYNVLPQGWKGSPAI
FQSSMTKILEPFRAKNPEIDIYQYMDDLYVGSDLEIGQHRAKIEELRDHLLKWGLTTPDK
KHQKEPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A L33LF G16A, L19V, E35D, M36I, R41K, I62V, L63P, H69K, T74S, L89M, I93L  
>SW070| codons 4-99
TLWQRPLVTIKIAGQVKEALLDTGADDTVFEDINLPGKWKPKMIGGIGGFVKVRQYDQVP
IEICGKKAIGSVLVGPTPANIIGRNMLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008