Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SW068 | SW068 | South Africa | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | EFV | NA |
| 2 | LPV+NVP | 23 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19I, M36I, R41K, L63T, H69K, T74S, L89M, I93L |
| >SW068| codons 4-99 TLWQRPLVTIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIT IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | V106A | F227L | S48T, V60I, K122E, D123S, K173A, Q174R, D177E, T200A, Q207E, R211K, V245E |
| >SW068| codons 40-247 EMEKEGKITKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG LKKKKSATVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAI FQSSMTKILEPFRARNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDK KHQKEPPLLWMGYELHPDKWTVQPIELP |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |