<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW057 sw057 South Africa 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65KR, M184MV   K103S, V106M   S48T, V60I, K122E, D123S, I142V, K166R, K173A, Q174A, D177E, I195L, Q197K, T200E, Q207A, R211K, F214L, D237E, V245Q  
>sw057| codons 40-247
EMEKEGKITKIGPENPYNTPIFAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LKKSKSMTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAI
FQSSMTRILEPFRAANPEIVIYQYVDDLYVGSDLELGKHREKIEELRAHLLKWGLTTPDK
KHQKEPPFLWMGYELHPEKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    V11F, I15V, M36I, R41K, Q61E, H69K, L89M, I93L R8A
>sw057| codons 7-99
QAPLFTIKVGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDEILIEI
CGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008