Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SW053 | sw053 | South Africa | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI | NA |
| 2 | 3TC+AZT+EFV | 27 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215Y | K103N, Y188L | V60I, K102Q, S162C, K173A, D177E, T200A, Q207E, V245Q |
| >sw053| codons 40-247 ELEKEGKISKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG LKQNKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAI FQCSMTKILEPFRAQNPEIVIYQYVDDLLVGSDLEIGQHRAKIEELREHLLRWGFYTPDK KHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, L19V, M36I, R41K, H69K, T74S, L89M, I93L |
| >sw053| codons 4-99 TLWQRPIVTIKIGGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |