Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SW049 | sw049 | South Africa | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NVP | 52 |
| 2 | 3TC+D4T+EFV | 52 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, V75M, M184V, L210W, T215Y | K103N, Y181YC, G190A | A98G | E44D, S48T, V60I, V118I, K122E, D123N, T139K, A158AS, S162G, K173A, Q174K, N175Y, D177E, I178M, T200A, Q207E, R211RK, D218DE, V245Q |
| >sw049| codons 40-247 ELEKDGKITKIGPENPYNTPIFAIKKKNSDKWRKLMDFRELNKRTQDFWEVQLGIPHPGG LKKNKSVTVLDVGDAYFSIPLDENFRKYTAFTIPSINNEKPGIRYQYNVLPQGWKGSPSI FQGSMTKILEPFRAKYPEMVICQYVDDLYVASDLEIGQHRAKIEELREHLWKWGFYTPEK KHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L19T, M36I, R41K, H69K, T74S, L89M, I93L |
| >sw049| codons 4-99 TLWQRPLVTIKIGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |