<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW043 sw043 South Africa 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI NA
2 3TC+AZT+EFV 132

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V A62V V106M V179D, F227L S48T, V60I, K103R, K122E, D123S, I135V, K173V, Q174K, D177E, T200A, I202V, Q207E, F214FL, L228R, V245Q  
>sw043| codons 40-247
ELEKEGKITKIGPENPYNTPIFVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LKKRKSMTVLDVGDAYFSVPLDESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAI
FQSSMTKILEPFRVKNPEIDIYQYVDDLYVGSDLEIGQHRAKVEELREHLLRWGLTTPDK
KHQKEPPLRWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K14R, I15V, L19I, M36I, R41K, H69K, I93L  
>sw043| codons 4-99
TLWQRPLVTIRVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008