<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW042 SW042 South Africa 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI NA
2 3TC+AZT+EFV 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   V106M V179VE E40R, S48T, S68G, K101Q, K102R, K104R, K122E, D123S, E138A, K173I, Q174QK, D177DE, T200A, Q207E, R211K, F214L, V245Q  
>SW042| codons 40-247
RMEKEGKITKIGPENPYNTPVFAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LQRKRSMTVLDVGDAYFSVPLDESFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAI
FQSSMTKILEPFRIKNPEIEIYQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDK
KHQKEPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, K14KR, L19I, E35D, M36MI, N37NS, R41K, K43KR, D60DE, Q61E, H69K, V82VI, L89M, I93L  
>SW042| codons 4-99
TLWQRPLVSIRIGGQIKEALLDTGADDTVLEDISLPGKWRPKMIGGIGGFIKVRQYEEIL
IEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008