Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SW039 | sw039 | South Africa | 2005 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+EFV | 52 |
| 2 | AZT+DDI+EFV | 29 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V106M | V179D, K238T | E40D, S48T, V60I, D121H, K122E, E138A, I142ST, K173A, Q174K, D177E, T200A, Q207E, F214L, V245Q |
| >sw039| codons 40-247 DMEKEGKITKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG LKKKKSMTVLDVGDAYFSVPLHEDFRKYTAFTIPSINNATPGTRYQYNVLPQGWKGSPAI FQSSMTKILEPFRAKNPEIDIYQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGLTTPDK KHQKEPPFLWMGYELHPDTWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19V, M36I, R41K, L63P, H69K, I93L |
| >sw039| codons 4-99 TLWQRPLVSIKVGGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIP IEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |