<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW039 sw039 South Africa 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+EFV 52
2 AZT+DDI+EFV 29

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    V106M V179D, K238T E40D, S48T, V60I, D121H, K122E, E138A, I142ST, K173A, Q174K, D177E, T200A, Q207E, F214L, V245Q  
>sw039| codons 40-247
DMEKEGKITKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LKKKKSMTVLDVGDAYFSVPLHEDFRKYTAFTIPSINNATPGTRYQYNVLPQGWKGSPAI
FQSSMTKILEPFRAKNPEIDIYQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGLTTPDK
KHQKEPPFLWMGYELHPDTWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19V, M36I, R41K, L63P, H69K, I93L  
>sw039| codons 4-99
TLWQRPLVSIKVGGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIP
IEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008