<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW034 sw034 South Africa 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP 81

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   Y181V   S48T, V90I, K122E, D123G, I135IM, I142T, S162Y, K166R, K173I, Q174R, D177E, V179I, T200A, E204EK, Q207E, R211K, E224EA, V245Q L205L*, L210L*
>sw034| codons 40-247
EMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAG
LKKKKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSMNNETPGTRYQYNVLPQGWKGSPAI
FQYSMTRILEPFRIRNPEIIIVQYVDDLYVGSDLEIGQHRAKIEK*REHL*KWGFTTPDK
KHQKAPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19T, M36I, L63P, H69K, I93L  
>sw034| codons 4-99
TLWQRPLVSIKVGGQTKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYDQIP
IEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008