<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW030 sw030 South Africa 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 53

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, K70KR, L74I, M184V V75IT, K219E L100I, K103N A98AG, P225H S48T, V60I, K122E, D123N, I135IMT, K173A, D177E, G196K, T200A, Q207E, R211K, V245Q  
>sw030| codons 40-247
EMEKEGKITKIGPENPYNTPIFAIKKKNSTRWRKITDFRELNKRTQDFWEVQLGIPHPGG
IKKNKSVTVLDVGDAYFSVPLDENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAI
FQSSMTKILEPFRAQNPEIVIYQYVDDLYVGSDLEIKQHRAKIEELREHLLKWGFTTPDE
KHQKEHPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19V, K20R, E35D, M36I, R41K, H69K, L89M, I93L  
>sw030| codons 4-99
TLWQRPLVSIKVGGQVREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008