<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW026 sw026 South Africa 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI+NVP 52
2 3TC+D4T+EFV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    K103N   S48T, V60I, K122E, D123N, S162C, K173A, Q174K, D177E, I178L, G196GE, T200A, Q207E, R211K, V245Q  
>sw026| codons 40-246
EMEKEGKITKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LKKNKSVTVLDVGDAYFSVPLDENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAI
FQCSMTKILEPFRAKNPELVIYQYMDDLYVGSDLEIEQHRAKIEELREHLLKWGFTTPDK
KHQKEPPFLWMGYELHPDKWTVQPIQL

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12E, K14R, I15V, G16E, L19T, K20R, M36I, P39S, R41K, D60E, H69K, L89M, I93L  
>sw026| codons 4-99
TLWQRPLVEIRVEGQTREALLDTGADDTVLEEINLSGKWKPKMIGGIGGFIKVRQYEQIL
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008