<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW025 sw025 South Africa 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T NA
2 3TC+AZT+NVP 25

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N P225H S48T, V60I, D121Y, K122E, I135R, S162A, K173A, D177E, T200A, Q207D, R211K, V245Q  
>sw025| codons 40-246
EMEKEGKITKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LKKNKSVTVLDVGDAYFSVPLYEDFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAI
FQASMTKILEPFRAQNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELRDHLLKWGFTTPDK
KHQKEHPFLWMGYELHPDKWTVQPIQL

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12D, I15V, L19T, M36I, R41K, L63P, H69K, L89M, I93L  
>sw025| codons 4-99
TLWQRPLVDIKVGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIP
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008