<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW014 sw014 South Africa 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T NA
2 3TC+AZT+NVP 79

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12P, I15V, L19T, K20KR, E35D, M36I, N37E, R41RK, D60E, Q61E, L63S, H69K, L89M, I93L  
>sw014| codons 4-99
TLWQRPLVPIKVGGQTREALLDTGADDTVLEDIELPGKWKPKMIGGIGGFIKVRQYEEIS
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, M184V   Y181C   S48T, V60I, K122E, D123G, I135R, A158T, K173T, D177E, I178M, T200A, Q207K, V245Q  
>sw014| codons 40-247
EMEKEGKITKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LKKKKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPTI
FQSSMTKILEPFRTQNPEMVICQYVDDLYVGSDLEIGQHRAKIEELRKHLLRWGFTTPDK
KHQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008