<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW012 sw012 South Africa 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+EFV 52

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, G16E, L19V, M36T, N37D, R41K, D60E, L63T, I64L, H69K, I72V, V77I, L89M, I93L  
>sw012| codons 4-99
TLWQRPLVSIKVEGQVKEALLDTGADDTVLEETDLPGKWKPKMIGGIGGFIKVRQYEQIT
LEICGKKAVGTVLIGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N V108I S48T, V60I, K122E, I135M, T165V, K173A, Q174D, D177E, T200I, Q207A, R211K, F214L, H221Y, V245Q  
>sw012| codons 40-247
EMEKEGKITKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LKKNKSVTILDVGDAYFSVPLDEDFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAI
FQSSMVKILEPFRADNPEIVIYQYVDDLYVGSDLEIGQHRIKIEELRAHLLKWGLTTPDK
KYQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008