Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SW008 | sw008 | South Africa | 2005 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI | NA |
| 2 | 3TC+AZT+EFV | 36 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215Y | V106M, M230L | S48T, K103R, K122E, T139M, S162C, K173A, D177E, T200A, I202V, Q207E, R211K, V245Q | E79EG |
| >sw008| codons 40-247 EMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRGLNKRTQDFWEVQLGIPHPAG LKKRKSMTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNEMPGIRYQYNVLPQGWKGSPAI FQCSMTKILEPFRAQNPEIVIYQYVDDLYVGSDLEIGQHRAKVEELREHLLKWGFYTPDK KHQKEPPFLWLGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, H69K, I93L |
| >sw008| codons 4-99 TLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |