<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW008 sw008 South Africa 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI NA
2 3TC+AZT+EFV 36

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215Y   V106M, M230L   S48T, K103R, K122E, T139M, S162C, K173A, D177E, T200A, I202V, Q207E, R211K, V245Q E79EG
>sw008| codons 40-247
EMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRGLNKRTQDFWEVQLGIPHPAG
LKKRKSMTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNEMPGIRYQYNVLPQGWKGSPAI
FQCSMTKILEPFRAQNPEIVIYQYVDDLYVGSDLEIGQHRAKVEELREHLLKWGFYTPDK
KHQKEPPFLWLGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, H69K, I93L  
>sw008| codons 4-99
TLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008