<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SW002 sw002 South Africa 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 58

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K101E, Y188L   K122E, D123DG, K173T, Q174K, V179I, T200A, Q207E, R211K, V245L G141GR
>sw002| codons 40-247
EMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LEKKKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSINNETPRIRYQYNVLPQGWKGSPAI
FQSSMTKILEPFRTKNPDIIIYQYVDDLLVGSDLEIGQHRAKIEELREHLLKWGFTTPDK
KHQKEPPFLWMGYELHPDKWTVQPILLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19V, M36I, N37D, R41K, D60E, Q61E, H69K, L89M, I93L  
>sw002| codons 4-99
TLWQRPLVSIKVGGQVKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYEEIL
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008