Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ICH29 | ICH029 | South Africa | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T | NA |
| 2 | 3TC+AZT+EFV | 52 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N, V106M | S48T, V60I, K122E, D123G, A158S, K173T, D177G, I178M, T200A, Q207A, R211K, V245K |
| >ICH029| codons 40-247 EMEKEGKITKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG LKKNKSMTVLDVGDAYFSVPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSI FQSSMTKILEPFRTQNPGMVIYQYVDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTPDK KHQKEPPFLWMGYELHPDKWTVQPIKLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19V, M36I, R41K, H69K, L89M, I93L |
| >ICH029| codons 4-99 TLWQRPLVSIKVGGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |