Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ICH28 | ICH028 | South Africa | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | 160 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I13V, I15V, L19I, M36I, N37S, R41K, L63V, H69K, T74S, L89M, I93L |
| >ICH028| codons 4-99 TLWQRPLVSVKVGGQIKEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYDQIV IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215F | L100I, K103N | K122E, I135L, E138R, K173A, D177G, T200A, E203K, Q207D, R211K, Q242R, V245R |
| >ICH028| codons 40-247 EMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG IKKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSLNNRTPGIRYQYNVLPQGWKGSPAI FQSSMTKILEPFRAQNPGIVIYQYVDDLYVGSDLEIGQHRAKIKELRDHLLKWGFFTPDK KHQKEPPFLWMGYELHPDKWTVRPIRLP |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |