<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
ICH27 ICH027 South Africa 2006 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NVP 1
2 3TC+D4T+EFV 29

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, T69~ K219R V106M, Y181C, G190A   S48T, V60I, K122E, D123S, K173A, Q174K, D177E, I195T, T200A, Q207E, R211K, L228R, V245Q  
>ICH027| codons 40-247
EMEKEGKITKIGPENPYNTPIFAIKRKDS~KWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LKKKKSMTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAI
FQSSMTKILEPFRAKNPEIVICQYMDDLYVASDLETGQHRAKIEELREHLLKWGFTTPDR
KHQKEPPFRWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, N37S, R41K, H69K, L89M, I93L  
>ICH027| codons 4-99
TLWQRPLVSIKVGGQIKEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008