Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ICH27 | ICH027 | South Africa | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | 1 |
| 2 | 3TC+D4T+EFV | 29 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, T69~ | K219R | V106M, Y181C, G190A | S48T, V60I, K122E, D123S, K173A, Q174K, D177E, I195T, T200A, Q207E, R211K, L228R, V245Q |
| >ICH027| codons 40-247 EMEKEGKITKIGPENPYNTPIFAIKRKDS~KWRKLVDFRELNKRTQDFWEVQLGIPHPAG LKKKKSMTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAI FQSSMTKILEPFRAKNPEIVICQYMDDLYVASDLETGQHRAKIEELREHLLKWGFTTPDR KHQKEPPFRWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, N37S, R41K, H69K, L89M, I93L |
| >ICH027| codons 4-99 TLWQRPLVSIKVGGQIKEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |