Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ICH25 | ICH25 | South Africa | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | 60 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N, Y188L | S48T, W88S, K122E, D123S, T139A, K173I, Q174K, T200A, I202V, Q207E, F214L, H221HY |
| >ICH25| codons 40-247 EMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFSEVQLGIPHPAG LKKNKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNEAPGIRYQYNVLPQGWKGSPAI FQSSMTKILEPFRIKNPDIVIYQYVDDLLVGSDLEIGQHRAKVEELREHLLRWGLTTPDK KYQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, K14R, I15V, L19I, E35D, M36I, R41K, K45R, D60E, I62V, G68E, H69R, L89M, I93L |
| >ICH25| codons 4-99 TLWQRPLVSIRVGGQIKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYEQVL IEICERKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |