Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ICH23 | ICH23 | South Africa | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T | NA |
| 2 | 3TC+AZT+EFV | 51 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, M184V | K219E | K103N, G190A | S48T, V60I, V90VI, K101Q, K122E, D123N, I135V, I142T, K173T, D177G, T200A, Q207A, R211K, V245Q |
| >ICH23| codons 40-247 EMEKEGKITKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAG LQKNKSVTVLDVGDAYFSVPLDENFRKYTAFTIPSVNNETPGTRYQYNVLPQGWKGSPAI FQSSMTKILEPFRTQNPGIVIYQYVDDLYVASDLEIGQHRAKIEELRAHLLKWGFTTPDE KHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, L19V, L63P, H69K, V77VI, I93L | I72Y |
| >ICH23| codons 4-99 TLWQRPLVSIKIGGQVKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQIP IEICGKKAYGTVLIGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |