Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1499 | CA9764 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDC | 44 |
| 2 | DDI | 126 |
| 3 | D4T | 52 |
| 4 | 3TC+D4T | 65 |
| 5 | 3TC+D4T+IDV | 58 |
| 6 | D4T+NFV+NVP | 44 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | G73S | E35D, N37Q, I62V, L63P, A71V, V77I, I93L |
| >CA9764| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDMQLPGRWKPKIIGGIGGFIKVRQYD QVPIEICGHKVISTVLIGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | Y181C, G190A | K20R, V35M, T39A, K43E, E44ED, V118I, D123E, D177E, E194X, G196E, E203K, Q207E, H208Y, R211EK, K223Q |
| >CA9320| codons 1-247 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALMEICAELEEDGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI CQYMDDLYVASDLXIEQHRTKIKELREYLWEWGFYTPDKKHQQEPPFLWMGYELHPDKWT VQPIVLP |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |