Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ICH20 | ICH20 | South Africa | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | 35 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, E35D, M36I, R41K, R57K, L63Q, H69K, T74S, L89M, I93L | W6V |
| >ICH20| codons 4-99 TLVQRPLVSIKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYDQIQ IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70KE, M184V | K103N | V108VI | E40D, S48T, V60I, S68G, K122E, D123G, I135T, K173A, Q174K, D177E, T200A, Q207E, R211K |
| >ICH20| codons 40-241 DMEKEGKITKIGPENPYNTPIFAIKKKDGTEWRKLVDFRELNKRTQDFWEVQLGIPHPAG LKKNKSVTILDVGDAYFSVPLDEGFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAI FQSSMTKILEPFRAKNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDK KHQKEPPFLWMGYELHPDKWTV |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |