Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ICH18 | ICH18 | South Africa | 2005 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+EFV | 39 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, L63A, H69K, L89M, I93L |
| >ICH18| codons 4-99 TLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIA IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74LV, M184V | G190Q | S48E, V118VI, D123E, I135IT, K173A, Q174K, D177E, I178IV, T200A, Q207E, V245Q | R143RT |
| >ICH18| codons 40-247 EMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAG LKKKKSVTVLDVGDAYFSIPLDKEFRKYTAFTIPSTNNETPGITYQYNVLPQGWKGSPAI FQSSMTKILEPFRAKNPEVVIYQYVDDLYVQSDLEIGQHRAKIEELREHLLRWGFTTPDK KHQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |