<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
ICH17 ICH17 South Africa 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 33

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, K70R, M184I, T215F D67G, K219E K103N, Y181C, G190A A98G, K238T T69N, R83RK, D121Y, K122E, D123G, Y144YF, S162C, K173A, D177E, T200A, E203EK, Q207E, R211K, K223E, L228H, Q242X, V245Q P157PS
>ICH17| codons 40-247
ELEKEGKISKIGPENPYNTPVFAIKKKGSNRWRKLVDFRELNKKTQDFWEVQLGIPHPGG
LKKNKSVTVLDVGDAYFSVPLYEGFRKYTAFTIPSINNETPGIRFQYNVLPQGWKGSSAI
FQCSMTKILEPFRAQNPEIVICQYIDDLYVASDLEIGQHRAKIKELREHLLKWGFFTPDE
KHQEEPPFHWMGYELHPDTWTVXPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, H69K, T74TS, L89M, I93L T96TI
>ICH17| codons 4-99
TLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCILNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008