Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ICH17 | ICH17 | South Africa | 2005 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | 33 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, K70R, M184I, T215F | D67G, K219E | K103N, Y181C, G190A | A98G, K238T | T69N, R83RK, D121Y, K122E, D123G, Y144YF, S162C, K173A, D177E, T200A, E203EK, Q207E, R211K, K223E, L228H, Q242X, V245Q | P157PS |
| >ICH17| codons 40-247 ELEKEGKISKIGPENPYNTPVFAIKKKGSNRWRKLVDFRELNKKTQDFWEVQLGIPHPGG LKKNKSVTVLDVGDAYFSVPLYEGFRKYTAFTIPSINNETPGIRFQYNVLPQGWKGSSAI FQCSMTKILEPFRAQNPEIVICQYIDDLYVASDLEIGQHRAKIKELREHLLKWGFFTPDE KHQEEPPFHWMGYELHPDTWTVXPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, H69K, T74TS, L89M, I93L | T96TI |
| >ICH17| codons 4-99 TLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCILNF |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |