Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ICH11 | ICH11 | South Africa | 2005 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | 1 |
| 2 | 3TC+D4T+EFV | 26 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K219E | K103N, G190GA | S48T, V60I, K122E, D123G, K173A, D177G, T200A, I202V, Q207E, R211K, V245K |
| >ICH11| codons 40-247 EMEKEGKITKIGPENPYNTPIFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAG LKKNKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAI FQSSMTKILEPFRAQNPGIVIYQYVDDLYVASDLEIGQHRAKVEELREHLLKWGFTTPDE KHQKEPPFLWMGYELHPDKWTVQPIKLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, K20R, M36I, R41K, H69K, L89M, I93L |
| >ICH11| codons 4-99 TLWQRPLVSIKVGGQIREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |