<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
ICH10 ICH10 South Africa 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 52
2 3TC+AZT+NVP 34

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70KR, M184V   K101E, V106M   K122E, D123S, K173V, Q174K, D177E, T200A, Q207G, R211K, F214L, V245Q  
>ICH10| codons 40-247
EMEKEGKISKIGPENPYNTPVFAIKKKDSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LEKKKSMTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAI
FQSSMTKILEPFRVKNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELRGHLLKWGLTTPDK
KHQKEPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, G16E, L19I, M36L, N37T, H69K, L89M, I93L  
>ICH10| codons 4-99
TLWQRPLVSIKVEGQIKEALLDTGADDTVLEELTLPGRWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008