Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ICH05 | ICH05 | South Africa | 2005 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+EFV | 28 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N | S48T, V60I, K122E, D123G, K166R, K173A, Q174S, D177E, T200A, Q207E, R211K, F214L, V245Q |
| >ICH05| codons 40-247 EMEKEGKITKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG LKKNKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAI FQSSMTRILEPFRASNPEIVIYQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDK KHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19T, E35D, N37S, R41K, L63P, H69K, V77I, L89M, I93L |
| >ICH05| codons 4-99 TLWQRPLVSIKVGGQTKEALLDTGADDTVLEDMSLPGKWKPKMIGGIGGFIKVRQYDQIP IEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |