<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
ICH03 ICH03 South Africa 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 D4T NA
2 3TC+AZT+NVP 87

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V T215I, K219E K103N, Y181C   S48T, E53D, V60I, K122E, D123G, T139R, K173A, Q174K, D177E, T200A, Q207D, R211K, V245Q  
>ICH03| codons 40-247
EMEKEGKITKIGPDNPYNTPIFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAG
LKKNKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSINNERPGIRYQYNVLPQGWKGSPAI
FQSSMTKILEPFRAKNPEIVICQYVDDLYVGSDLEIGQHRAKIEELRDHLLKWGFITPDE
KHQKEPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I13IL, I15V, L19I, E35D, M36I, R41K, H69K, T74S, L89M, I93L  
>ICH03| codons 4-99
TLWQRPLVSLKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYDQIL
IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008