Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ICH03 | ICH03 | South Africa | 2005 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T | NA |
| 2 | 3TC+AZT+NVP | 87 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | T215I, K219E | K103N, Y181C | S48T, E53D, V60I, K122E, D123G, T139R, K173A, Q174K, D177E, T200A, Q207D, R211K, V245Q |
| >ICH03| codons 40-247 EMEKEGKITKIGPDNPYNTPIFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAG LKKNKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSINNERPGIRYQYNVLPQGWKGSPAI FQSSMTKILEPFRAKNPEIVICQYVDDLYVGSDLEIGQHRAKIEELRDHLLKWGFITPDE KHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I13IL, I15V, L19I, E35D, M36I, R41K, H69K, T74S, L89M, I93L |
| >ICH03| codons 4-99 TLWQRPLVSLKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |