Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ICH02 | ICH02 | South Africa | 2005 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | 26 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, M184V | K101E, V106M, G190A | S48T, E53D, V60I, R83K, K122E, I135V, K173A, Q174R, D177E, I178L, E194Q, T200A, Q207E, R211K, V245Q |
| >ICH02| codons 40-247 EMEKEGKITKIGPDNPYNTPIFAIKKKNSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAG LEKKKSMTVLDVGDAYFSVPLDEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAI FQSSMTKILEPFRARNPELVIYQYVDDLYVASDLQIGQHRAKIEELREHLLKWGFTTPDK KHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, L63P, C67Y, H69K, L89M, I93L |
| >ICH02| codons 4-99 TLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIP IEIYGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |