<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
ICH02 ICH02 South Africa 2005 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, M184V   K101E, V106M, G190A   S48T, E53D, V60I, R83K, K122E, I135V, K173A, Q174R, D177E, I178L, E194Q, T200A, Q207E, R211K, V245Q  
>ICH02| codons 40-247
EMEKEGKITKIGPDNPYNTPIFAIKKKNSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAG
LEKKKSMTVLDVGDAYFSVPLDEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAI
FQSSMTKILEPFRARNPELVIYQYVDDLYVASDLQIGQHRAKIEELREHLLKWGFTTPDK
KHQKEPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, L63P, C67Y, H69K, L89M, I93L  
>ICH02| codons 4-99
TLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIP
IEIYGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Marconi, VC Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008