Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ICH01 | ICH01 | South Africa | 2005 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI | NA |
| 2 | 3TC+AZT+EFV | 111 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | T215TI, K219E | K103N, Y188L | S48T, A98S, K122E, D123E, K173A, D177E, I178L, T200A, E204K, Q207E, R211RK, V245Q | K102T |
| >ICH01| codons 40-247 EMEKEGKITKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPSG LKTNKSVTVLDVGDAYFSVPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAI FQSSMTKILEPFRAQNPELVIYQYVDDLLVGSDLEIGQHRAKIEKLREHLLKWGFITPDE KHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, K14R, I15V, L19I, K20R, E35D, M36I, R41K, H69K, L89M, I93L |
| >ICH01| codons 4-99 TLWQRPLVSIRVGGQIREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Marconi, VC | Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. | Clin Infect Dis, 2008 |