Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1498 | CA9747 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T | 61 |
| 2 | AZT | 44 |
| 3 | 3TC+AZT+SQV | 82 |
| 4 | 3TC+AZT | 6 |
| 5 | 3TC+AZT+IDV | 42 |
| 6 | D4T+NFV+NVP | 37 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | G73S | L10I, L63P, K70R, A71V, I72L, V77VI |
| >CA9747| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHRVLSTVLIGPTPVNIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | K103N, Y181C | K20KR, E28A, K122E, S162SC, E169D, Q197E, Q207E, R211K, A272P |
| >CA9289| codons 1-276 PISPIETVPVKLKPGMDGPRVKQWPLTAEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRKQNPDIVI CQYMDDLYVGSDLEIGEHRTKIEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKV |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |