Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA3920 | CA9693 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 72 |
| 2 | AZT+DDC | 134 |
| 3 | 3TC+D4T | 36 |
| 4 | 3TC+AZT+IDV | 16 |
| 5 | 3TC+AZT+NFV | 46 |
| 6 | NVP+3TC+D4T+NFV | 51 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | I13V, N37CS, L63P, I64V, A71V, V77I |
| >CA9693| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADNTVLEEMCLPGRWKPKMIGGIGGFIKVRQYD QIPVEICGHKVIGTVLIGPTPVNIIGRDLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | T215TAIV, K219Q | K103KN, V106VA, Y181YC, G190GA | V35M, I135IM, K166R, V179VI, G196E, Q197K, F214FL, D218E, D237DN, V245T, E248D |
| >CA37718| codons 1-249 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSATVLDVGDAYFSVPL DKDFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIII CQYVDDLYVASDLEIEKHRTKIEELRQHLLRWGLVTPEQKHQKEPPFLWMGYELHPNKWT VQPITLPDK |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |