Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA30189 | CA96563 | U.S. | 2008 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NFV | 170 |
| 2 | 3TC+ABC+NFV | 82 |
| 3 | EFV+FTC+TDF | 76 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R | L100I, Y188L | V90I, K122E, D177E, I178M, L210S, R211Q, K277R, V292I, I293V |
| >CA96563| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKRKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGIKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI YQYMDDLLVGSDLEIGQHRTKIEELRQHLSQWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEIVPLTEEAE L |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, G16A |
| >CA96562| codons 1-99 PQITLWQRPLVTIKVAGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Melikian, GL | Standardized comparison of the relative impacts of HIV-1 reverse transcriptase (RT) mutations on nucleoside RT inhibitor susceptibility. | AAC, 2012 |