Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA3979 | CA9549 | U.S. | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 161 |
| 2 | 3TC+AZT+IDV | 13 |
| 3 | 3TC+AZT+SQV | 26 |
| 4 | 3TC+AZT+NFV | 65 |
| 5 | 3TC+DDI+NVP+RTV+SQV | 16 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30DN, L90M | N88D | K20I, E35D, M36IV, I62V, L63P, H69NT, A71AV |
| >CA9549| codons 1-99 PQITLWQRPLVTIKIGGQLIEALLDTGADNTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGNKVIGTVLVGPTPVNIIGRDLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R | K103N, Y181YC | K20R, T69N, R83K, K122E, D123E, D177E, I178M, F214L | K219KI |
| >CA9226| codons 1-219 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSNRWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI CQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDI |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |