<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA4004 CA9543 U.S. 1998 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT 73
2 3TC+AZT+IDV 134
3 D4T+DDI+EFV+NFV 11

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, V82A K43T K20KR, M36I, M46X, I62V, L63P, H69HY, A71V, Q92E  
>CA9543| codons 1-99
PQITLWQRPLVTIKIGGQLREALLDTGADDTILEEINLPGRWTPKXIGGIGGFIKVRQYD
QVPIEICGYKVIGTVLVGPTPANIIGRNLLTEIGCTLNF

References
Author Title Citation
Gonzales, MJ HIV-1 reverse transcriptase and protease subtypes: Classification, amino acid mutation patterns, and prevalence in a northern California clinic-based population. J Infect Dis, 2001
Wu, TD Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments. J Virol, 2003
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005