<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
IR26B IR26B Russia 2000 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, I15M, E35D, M36I, R41K, H69K, V77I, L89M, I93L, T96S  
>IR26B| codons 1-99
PQITLWQRPLVTVRMGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCSLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
  A62V Y188YC   K11T, V21G, V35I, E36D, T39K, K43R, V106VL, D121DN, K122E, D123S, A158S, R172RK, K173L, Q174K, D177E, Q207A, H208HY, R211S E44Q, R143RI, F160FL, D218H, Q242N
>IR26B| codons 1-263
PISPIETVPVTLKPGMDGPKGKQWPLTEEKIKALIDICKEMERQGKISKIGPENPYNTPV
FVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSLTVLDVGDAYFSVPL
NESFRKYTAFTIPSINNETPGIIYQYNVLPQGWKGSPSILQSSMTKILEPFKLKNPEIVI
YQYMDDLCVGSDLEIGQHRTKIEELRAYLLSWGFTTPHKKHQKEPPFLWMGYELHPDKWT
VNPIVLPEKDSWTVNDIQKLVGK

References
Author Title Citation
Vazquez de Parga, E Analysis of drug resistance-associated mutations in treatment-naive individuals infected with different genetic forms of HIV-1 circulating in countries of the former Soviet Union. J Med Virol, 2005