<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BRSAP02 04BRSAP02 Brazil 2004 HIV1 B PBMC None

Treatment History
Order Regimen Weeks
1 AZT|DDI|IDV|NFV|RTV NA
2 3TC+D4T+LPV+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L   Y181C   T7P, K122E, I135T, K166R, E169D, D177E  
>04BRSAP02| codons 1-233
PISPIEPVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILDPFRKQNPEIVI
CQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A L24I L10I, I13V, G17D, K20M, E35D, M36I, K55R, R57K, D60E, I62V, L63P  
>04BRSAP02| codons 6-99
WQRPIVTVKIGDQLMEALIDTGADDTVLEDINLPGRWKPKMIGGIGGFVRVKQYEQVPIE
ICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Eyer-Silva, WA Autochthonous horizontal transmission of a CRF02_AG strain revealed by a human immunodeficiency virus type 1 diversity survey in a small city in inner state of Rio de Janeiro, Southeast Brazil. Mem Ins Oswaldo Cruz, 2007