Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CHB253M | CHB253M | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | 1 |
| 2 | None | 12 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6KN, V35T, T39E, S48T, K104R, K122E, E138A, K173IMT, Q174K, T200TA, I202V, Q207A, R211KT, F214L, V245Q, E248DN, A272P, K277R, T286A, E291D, V292I, I293V |
| >CHB253M| codons 1-333 PISPINTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDIVI YQYMDDLYVGSDLEIGQHRAKVEELRAHLLTWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, K20R, E35D, M36I, R41K, D60E, Q61E, H69K, L89M, I93L |
| >CHB253M| codons 1-99 PQITLWQRPLVSIKVGGQIREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE EILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Martinson, NA | Selection and persistence of viral resistance in HIV-infected children after exposure to single-dose nevirapine. | JAIDS, 2007 |