Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CHB188M | CHB188M | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | 1 |
| 2 | None | 12 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I13V, I15V, G16E, L19I, E35EK, M36I, R41K, D60E, H69K, L89I, I93L, L97I |
| >CHB188M| codons 1-99 PQITLWQRPLVSVKVEGQIKEALLDTGADDTVLEKINLPGKWKPKMIGGIGGFIKVRQYE QILIEICGKKAIGTVLVGPTPVNIIGRNILTQLGCTINF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6D, K20KR, V35T, E36A, T39E, E40D, S48T, V60I, K122E, D123N, A158S, K166R, K173T, T200A, Q207E, V245L, D250E, S251D, A272P, K277T, T286A, E291D, V292I, I293V |
| >CHB188M| codons 1-333 PISPIDTVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEDMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTRILEPFRTQNPDIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPILLPEKEDWTVNDIQKLVGKLNWASQIYPGIKVTQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
References
| Author | Title | Citation |
| Martinson, NA | Selection and persistence of viral resistance in HIV-infected children after exposure to single-dose nevirapine. | JAIDS, 2007 |