Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| KEH181B | KEH181B | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | 1 |
| 2 | None | 12 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y181C | V35T, E36A, T39E, S48T, V60I, K122E, D123G, I135V, I142L, K173A, Q174E, D177E, T200A, Q207E, V245Q, A272P, T286A, E291D, V292I, I293V, L303M, E312D |
| >KEH181B| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSVNNETPGLRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAENPEIVI CQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE LEMAENREILKDPVHGVYYDPSKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, R57*, L63P, H69K, L89I, I93L |
| >KEH181B| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKV*QYD QIPIEICGKKAIGTVLVGPTPVNIIGRNILTQLGCTLNF |
References
| Author | Title | Citation |
| Martinson, NA | Selection and persistence of viral resistance in HIV-infected children after exposure to single-dose nevirapine. | JAIDS, 2007 |