<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
KEH181M KEH181M South Africa 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NVP 1
2 None 12

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, L63P, H69K, K70KR, L89I, I93L  
>KEH181M| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKRAIGTVLVGPTPVNIIGRNILTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    K103KN, Y181YC, G190GA   V35T, E36A, T39E, S48T, V60I, K122E, D123G, I135V, I142L, K166KR, K173A, Q174E, D177E, T200A, Q207E, V245Q, A272P, K277KR, T286A, E291D, V292I, I293V, L303LM, E312D, Q334QH  
>KEH181M| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSVNNETPGLRYQYNVLPQGWKGSPAIFQSSMTRILEPFRAENPEIVI
CQYMDDLYVASDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LEMAENREILKDPVHGVYYDPSKDLIAEIQKQGH

References
Author Title Citation
Martinson, NA Selection and persistence of viral resistance in HIV-infected children after exposure to single-dose nevirapine. JAIDS, 2007