<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CHB398B CHB398B South Africa 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NVP 1
2 None 12

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    Y181C   V35T, E36A, T39E, S48E, V60I, K122E, D123S, I135R, S162A, K173A, D177E, Q207A, R211K, V245Q, D250E, A272P, E291D, V292I, I293V, Q334L K13R
>CHB398B| codons 1-335
PISPIETVPVKLRPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKIEKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAQNPEIVI
CQYMDDLYVGSDLEIGQHRTKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGLG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, E35D, M36I, R41K, I62V, L63P, H69K, A71T, L89M, I93L  
>CHB398B| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QVPIEICGKKTIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Martinson, NA Selection and persistence of viral resistance in HIV-infected children after exposure to single-dose nevirapine. JAIDS, 2007