<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CHB374M CHB374M South Africa 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NVP 1
2 None 12

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, K20R, E34K, E35N, M36I, P39Q, R41K, H69K, L89I, I93L  
>CHB374M| codons 1-99
PQITLWQRPLVSIKVGGQIREALLDTGADDTVLKNINLQGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNILTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
      K238T V35T, E36A, T39E, S48T, K122E, D123G, S162C, K173A, Q174K, D177E, T200A, E203G, Q207E, R211K, V245Q, D250E, K277R, T286A, E291D, V292I, I293V, I326V, Q334E  
>CHB374M| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIGELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDTWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGEG

References
Author Title Citation
Martinson, NA Selection and persistence of viral resistance in HIV-infected children after exposure to single-dose nevirapine. JAIDS, 2007