Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CHB374M | CHB374M | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | 1 |
| 2 | None | 12 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, K20R, E34K, E35N, M36I, P39Q, R41K, H69K, L89I, I93L |
| >CHB374M| codons 1-99 PQITLWQRPLVSIKVGGQIREALLDTGADDTVLKNINLQGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNILTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K238T | V35T, E36A, T39E, S48T, K122E, D123G, S162C, K173A, Q174K, D177E, T200A, E203G, Q207E, R211K, V245Q, D250E, K277R, T286A, E291D, V292I, I293V, I326V, Q334E |
| >CHB374M| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIGELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDTWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLVAEIQKQGEG |
References
| Author | Title | Citation |
| Martinson, NA | Selection and persistence of viral resistance in HIV-infected children after exposure to single-dose nevirapine. | JAIDS, 2007 |