Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| KEH2B | KEH2B | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | 1 |
| 2 | None | 12 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y181C, Y188YC | K20R, V35T, T39E, S48T, V60I, K122E, I135IV, S162Y, K173T, T200A, Q207E, R211K, K223R, V245Q, A272P, I274V, Q278N, T286A, E291D, V292I, I293V, D324E |
| >KEH2B| codons 1-334 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRTQNPDIVI CQYMDDLCVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQREPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGVKVKNLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKELIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| Q7R, K14R, L19I, M36I, R41K, H69K, L89M, I93L |
| >KEH2B| codons 1-99 PQITLWRRPLVTIRIGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Martinson, NA | Selection and persistence of viral resistance in HIV-infected children after exposure to single-dose nevirapine. | JAIDS, 2007 |